The Fresno County Department of Public Health (FCDPH) announced on Monday that the county has recorded its first human fatality from West Nile virus (WNV) in 2025. This brings the total number of WNV-related deaths in California this year to three, with 43 confirmed human cases statewide.
In Fresno County, health officials have identified five additional positive human cases so far this year. The department expects more cases may be reported through October.
West Nile virus was first detected in California in 2003. Since then, over 8,000 people have been infected and more than 400 deaths have occurred across the state.
“Our heartfelt condolences go out to the family and friends of this individual. We need to stay vigilant as mosquitoes may continue to test positive for WNV in the County. The infected mosquitoes may cause severe illnesses, including WNV infection, which can require hospitalization and can result in death,” said FCDPH Interim Health Officer Dr. Rais Vohra. “It is very important that we take steps to minimize mosquito bites, especially when there is an increase in mosquito activity during these warmer temperatures.”
Symptoms of West Nile virus often include fever, headache, body aches, fatigue, nausea, vomiting, swollen lymph nodes and rash.
The virus spreads primarily through mosquito bites after mosquitoes feed on infected birds. These mosquitoes can then transmit the virus to humans and other animals.
Fresno County health officials recommend residents take precautions against mosquito bites and potential infection from West Nile virus.


